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A study of more than 7,000 British civil servants finds that age-related declines in cognitive ability start as early as 45. The results suggest that efforts to head off mental problems late in life need to begin in middle age, the study's authors write at the end of their paper.

Men are diagnosed with mild cognitive impairment earlier than women, perhaps because of physical health issues. That's the word from a study of older people in Minnesota. But by their mid-80s, both men and women suffer the same level of loss of thinking capacity, the researchers found.

Time is running out for Christmas shoppers, but even more so for those who need to ship those presents. UPS hired about 55,000 seasonal workers around the world to help handle the holiday volume, including 800 at the air hub in Louisville, Kentucky.

Political figures send out holiday cards just like everyone else. ...Well, maybe not exactly like everyone else.

Hugo Chávez, who had a tumor removed in June, said he had no proof but said he wouldn't be surprised if the U.S. had invented technology to spread cancer.

The late 19th century British Arctic explorer was many things, but not actually a lord.

Democrats are surely relieved to have held onto the W. Virginia governorship, with Tuesday's special election victory by acting Gov. Earl Ray Tomblin over Republican Bill Maloney. But it was a narrow 50 percent to 47 percent win that could portend trouble when Tomblin once again stands for election in 14 months.

The $447 billion plan is likely to be rejected later today when the Senate holds a key procedural vote. Democrats have a "Plan B," though. They're looking at breaking up the measure into smaller pieces that may stand better chances of passage.

Authorities said employees were buying and selling prescription drugs like Oxycontin and Xanax inside the plant that manufactures CH-47 Chinooks and other military aircraft. The FBI and DEA said they made the arrests using evidence gathered during undercover operations.

The disgraced former Illinois governor didn't apologize. Instead, he said he was "on the right side of the law."